Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259536 | 1.00 | RAB9A (0.59) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL1259531 | 0.85 | ALDH1A1 (0.60) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL176880 | 0.83 | TDP1 (0.56) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL176878 | 0.83 | TDP1 (0.56) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL8456522 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL7922499 | 0.76 | ALDH1A1 (0.64) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL39472 | 0.76 | HPGD (0.78) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL10728673 | 0.76 | ALDH1A1 (0.58) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL9187561 | 0.75 | NPC1 (1.00) | RAB9ANPC1RECQLALDH1A1TDP1 | |
| SCHEMBL26509809 | 0.74 | ALDH1A1 (0.67) | RAB9ANPC1RECQLALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025604-A9 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-05-02 | — | — | WO | claimed |
| WO-2024025604-A2 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | claimed |
| EP-3464384-A1 | FUSION PROTEIN CONSTRUCT | Northwestern University (US) | 2019-04-10 | — | — | EP | claimed |
| WO-2017214151-A1 | FUSION PROTEIN CONSTRUCT | NORTHWESTERN UNIVERSITY (US) | 2017-12-14 | — | — | WO | claimed |
| US-20250326723-A1 | Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly | UNIV NORTHWESTERN (US) | 2025-10-23 | — | — | US | disclosed |
| WO-2024025604-A9 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024025604-A2 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11667648-B2 | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements | PROMEGA CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| CN-112996497-A | Morphic forms of complement factor D inhibitors | 艾其林医药公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2021056811-A1 | IMINE SALT DERIVATIVE AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR NICOTINE | 深圳黑尔格科技有限公司 | 2021-04-01 | — | — | WO | disclosed |
| US-20200199140-A1 | CELL-PERMEABLE, CELL-COMPATIBLE, AND CLEAVABLE LINKERS FOR COVALENT TETHERING OF FUNCTIONAL ELEMENTS | PROMEGA CORPORATION | 2020-06-25 | — | — | US | disclosed |
| US-10618907-B2 | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements | PROMEGA CORPORATION (US) | 2020-04-14 | — | — | US | disclosed |
| US-20030119054-A1 | Polypeptide immobilization | NATIONAL SCIENCE FOUNDATION | 2003-06-26 | — | — | US | disclosed |
| EP-0946755-A4 | METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING | MAXYGEN INC (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0946755-A1 | METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING | Maxygen, Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027230-A1 | METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING | MAXYGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |
| EP-0362304-B1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | IGEN INC (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0362304-A4 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | — | 1991-04-10 | — | — | EP | disclosed |
| EP-0362304-A1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES. | IGEN INC (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989005977-A1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | IGEN, INC. (US) | 1989-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199140-A1 | CELL-PERMEABLE, CELL-COMPATIBLE, AND CLEAVABLE LINKERS FOR COVALENT TETHERING OF FUNCTIONAL ELEMENTS | LNPK, EPCAM, AFG3L2 | RAB9A 1949/4885NPC1 1091/4885RECQL 3094/4885 |
| US-20030119054-A1 | Polypeptide immobilization | SURF4, QPCTL, QPCT | RAB9A 4710/4885NPC1 3727/4885RECQL 3512/4885 |
| US-11667648-B2 | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements | LNPK, EPCAM, AFG3L2 | RAB9A 1949/4885NPC1 1091/4885RECQL 3094/4885 |
| US-10618907-B2 | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements | LNPK, EPCAM, AFG3L2 | RAB9A 1949/4885NPC1 1091/4885RECQL 3094/4885 |
| US-20250326723-A1 | Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly | CRABP2, RARB, RARA | RAB9A 1966/4885NPC1 3855/4885RECQL 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.