Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 3/20 | 0.47 |
| ▸ | TPMT | P51580 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616095 | 0.88 | STIM1 (0.54) | ERN1FNTAFNTBPGGT1BPTK2 | |
| SCHEMBL4063179 | 0.84 | STIM1 (0.64) | ERN1FNTAFNTBPGGT1BPTK2 | |
| SCHEMBL4121356 | 0.83 | ERN1 (0.64) | ERN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31431633 | 0.83 | ERN1 (0.64) | ERN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12844716 | 0.80 | TUBB4A (0.51) | STIM1ORAI1AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL417159 | 0.80 | KAT6A (0.61) | ERN1FNTAFNTBPGGT1BSTIM1 | |
| SCHEMBL28180336 | 0.80 | CA12 (0.50) | ERN1FNTAFNTBPGGT1BPTK2 | |
| SCHEMBL12599367 | 0.79 | ALDH1A1 (0.56) | ERN1FNTAFNTBPGGT1BPDE4D | |
| SCHEMBL205626 | 0.79 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL17799599 | 0.79 | KAT6A (0.63) | ERN1FNTAFNTBPGGT1BSTIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |