Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268780 | 0.91 | TSHR (0.61) | L3MBTL1HTTTSHRHPGDHCAR3 | |
| SCHEMBL12062843 | 0.89 | L3MBTL1 (0.55) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL4927777 | 0.88 | NAAA (0.57) | L3MBTL1THRBHTTTSHRALDH1A1 | |
| SCHEMBL29846373 | 0.84 | HSD17B10 (0.46) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL14414983 | 0.82 | POLB (0.43) | POLBL3MBTL1THRBRECQLTDP1 | |
| SCHEMBL10440167 | 0.82 | NAAA (0.57) | L3MBTL1THRBHTTTSHRALDH1A1 | |
| SCHEMBL3754605 | 0.82 | NAAA (0.57) | L3MBTL1THRBHTTTSHRALDH1A1 | |
| SCHEMBL15942987 | 0.80 | HSD17B10 (0.43) | POLBL3MBTL1TDP1HTTTSHR | |
| SCHEMBL1698253 | 0.80 | LMNA (0.59) | KDM4EMYCLMNARAB9AMAPT | |
| SCHEMBL17361214 | 0.80 | NAAA (0.55) | POLBL3MBTL1THRBTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892274-B1 | Water repellent treatment using polysiloxanes containing carboxyl groups | LANXESS DEUTSCHLAND GMBH (DE) | 2011-06-29 | — | — | EP | disclosed |
| EP-1892274-A2 | Water repellent treatment using polysiloxanes containing carboxyl groups | Lanxess Deutschland GmbH (DE) | 2008-02-27 | — | — | EP | disclosed |