Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174723 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL1852267 | 0.83 | KMT2A (0.33) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL15690624 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL29740018 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL16038153 | 0.81 | TSHR (0.48) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL25300036 | 0.81 | TDP1 (0.45) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL8809569 | 0.79 | MAPT (0.52) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL25377636 | 0.78 | S100A4 (0.42) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL30510054 | 0.78 | S100A4 (0.42) | ALDH1A1TDP1KMT2AMEN1HPGD | |
| SCHEMBL29020409 | 0.76 | S100A4 (0.35) | ALDH1A1TDP1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | claimed |
| CN-116444436-B | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2026-04-03 | — | — | CN | disclosed |
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022226133-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-27 | — | — | WO | disclosed |
| EP-2967073-B9 | LXR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-04-10 | — | — | EP | disclosed |
| US-10123978-B2 | Patch for treating dermatophytosis | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-2881114-B1 | ANTI-TRICHOPHYTIC ADHESIVE PATCH | MEIJI SEIKA PHARMA CO LTD (JP) | 2018-09-05 | — | — | EP | disclosed |
| EP-2967073-B1 | LXR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-08-01 | — | — | EP | disclosed |
| WO-2012007006-A1 | TRIAZOLO- AND PYRAZOLOQUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITOR | H. LUNDBECK A/S (DK) | 2012-01-19 | — | — | WO | disclosed |
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| US-20090221555-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS | CEPHALON, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| CN-101087773-A | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-12 | — | — | CN | disclosed |
| EP-1807406-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047503-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA (BE) | 2006-05-04 | — | — | WO | disclosed |
| US-20050113566-A1 | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-05-26 | — | — | US | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221555-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS | ALK, MET, RET | ALDH1A1 77/4885TDP1 1885/4885KMT2A 501/4885 |
| US-10123978-B2 | Patch for treating dermatophytosis | DPM1, KRT18, LCP1 | ALDH1A1 3414/4885TDP1 3211/4885KMT2A 183/4885 |
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | IL6, IL6ST, IL36G | ALDH1A1 2068/4885TDP1 3358/4885KMT2A 4050/4885 |
| US-20050113566-A1 | Inhibitors of C-FMS kinase | ALK, TYRO3, PDGFRB | ALDH1A1 2507/4885TDP1 4349/4885KMT2A 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.