Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604897 | 0.80 | MAPT (0.51) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL12604898 | 0.77 | BCL2 (0.67) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL29456701 | 0.71 | PABPC1 (0.72) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL13045522 | 0.71 | PABPC1 (0.72) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL1514307 | 0.68 | KMT2A (0.60) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL20835013 | 0.67 | MAPT (0.66) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL24334669 | 0.66 | MAPT (0.64) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL13006706 | 0.66 | SMN1; SMN2 (1.00) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL16582580 | 0.66 | KEAP1 (0.78) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL17322323 | 0.66 | PABPC1 (0.64) | MAPTPABPC1KDM4ESMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085431-B1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT FINANCE BVI LTD (VG) | 2011-06-29 | — | — | EP | disclosed |
| US-20090255440-A1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT INTERNATIONAL LTD. | 2009-10-15 | — | — | US | disclosed |
| EP-2085431-A1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT INTERNATIONAL LTD. (CH) | 2009-08-05 | — | — | EP | disclosed |