SCHEMBL1277091

SCHEMBL1277091

CCCCCCCN1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 2/20 0.75
▸ GNAI3 P08754 6/20 0.59
▸ GNAO1 P09471 6/20 0.59
▸ GNAI1 P63096 6/20 0.59
▸ LTA4H P09960 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.47
▸ BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL634336 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1262658 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11226591 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1262669 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11210977 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL9641523 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL23682856 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1260762 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL22151380 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11224880 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135323-A Pharmaceutical composition 深圳市药欣生物科技有限公司 2022-09-30 — — CN claimed
CN-104073901-B The application in polyurethane composite fibre of the nitrogen containing plasma liquid 杭州师范大学 2017-01-04 — — CN claimed
EP-4711502-A1 ELECTROLYSIS DEVICE AND METHOD FOR MANUFACTURING ELECTROLYSIS DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2026-03-18 — — EP disclosed
EP-4527987-A2 ELECTROLYSIS DEVICE Kabushiki Kaisha Toshiba (JP) 2025-03-26 — — EP disclosed
US-20250092548-A1 ELECTROLYSIS DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2025-03-20 — — US disclosed
US-12018017-B2 Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2024-06-25 — — US disclosed
EP-4350049-A2 AMMONIA MANUFACTURING APPARATUS AND AMMONIA MANUFACTURING METHOD KABUSHIKI KAISHA TOSHIBA (JP) 2024-04-10 — — EP disclosed
US-20240110293-A1 AMMONIA MANUFACTURING APPARATUS AND AMMONIA MANUFACTURING METHOD KABUSHIKI KAISHA TOSHIBA (JP) 2024-04-04 — — US disclosed
US-20230382889-A1 COMPOUNDS FOR INHIBITING KIF18A VOLASTRA THERAPEUTICS, INC. (US) 2023-11-30 — — US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 — — US disclosed
CN-113382859-B Surface protective film 日东电工株式会社 2023-08-11 — — CN disclosed
WO-2005092854-A1 BICYCLIC SUBSTITUTED INDOLE-DERIVATIVE STEROID HORMONE NUCLEAR RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-10-06 — — WO disclosed
WO-2005070916-A1 THIOPHENE AND FURAN COMPOUNDS ELI LILLY AND COMPANY (US) 2005-08-04 — — WO disclosed
WO-2005066153-A1 TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-07-21 — — WO disclosed
WO-2004067529-A1 INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS ELI LILLY AND COMPANY (US) 2004-08-12 — — WO disclosed
CN-1061567-C modified ion exchange resin and application thereof MITSUBISHI CHEM CORP (JP) 2001-02-07 — — CN disclosed
CN-1119129-A modified ion exchange resin and application thereof MITSUBISHI CHEM CORP (JP) 1996-03-27 — — CN disclosed
US-4980346-A N-ALKYL(ENE)-N-(O,O-DISUBSTITUTED-THIOPHOSPHORYL)-N',N' -SUBSTITUTED GLYCINE AMIDE DERIVATIVES ESZAKMAGYARORSUAGI VEGYIMUVEK (HU) 1990-12-25 — — US disclosed
US-4220764-A Preparation of tertiary heterocyclic amines UOP INC. (US) 1980-09-02 — — US disclosed
US-4096150-A Process for manufacture of tertiary amines RHONE-PROGIL (FR) 1978-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382889-A1 COMPOUNDS FOR INHIBITING KIF18A KIF18A, KIF18B, KIF2C HRH3 4292/4885GNAI3 525/4885GNAO1 1716/4885
US-12018017-B2 Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof BAD, CASP1, BAX HRH3 4103/4885GNAI3 1630/4885GNAO1 2416/4885
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 HRH3 2171/4885GNAI3 1283/4885GNAO1 2211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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