Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420524 | 0.68 | HTR2C (0.37) | PARP1MAOAMAOBFTONFKB1 | |
| SCHEMBL216625 | 0.67 | — | — | |
| SCHEMBL4429415 | 0.67 | PAX8 (0.48) | MAOAMAOBFTONFKB1ALDH1A1 | |
| SCHEMBL23219216 | 0.67 | MAOA (0.42) | MAOAMAOBFTONFKB1HTR2C | |
| SCHEMBL29591435 | 0.67 | MAOA (0.42) | MAOAMAOBFTONFKB1HTR2C | |
| SCHEMBL11480070 | 0.67 | GSK3B (0.42) | PARP1GSK3BALDH1A1CYP3A4HPGD | |
| SCHEMBL14221224 | 0.65 | CYP3A4 (0.39) | MAOAMAOBFTONFKB1ALDH1A1 | |
| SCHEMBL16564370 | 0.65 | GSK3B (0.53) | PARP1GSK3BALDH1A1CYP3A4HPGD | |
| SCHEMBL1238307 | 0.65 | GSK3B (0.53) | PARP1GSK3BALDH1A1CYP3A4HPGD | |
| SCHEMBL8861466 | 0.65 | PARP1 (0.52) | PARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284019-B | Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative | 安徽工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-116284019-A | Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative | 安徽工业大学 | 2023-06-23 | — | — | CN | claimed |
| US-12545700-B2 | Excitonic quantum computing via aggregate-aggregate coupling | BOISE STATE UNIVERSITY (US) | 2026-02-10 | — | — | US | disclosed |
| EP-4674855-A1 | A COMPOUND, AN ORGANIC LIGHT EMITTING DIODE COMPRISING THE DERIVATES, A USE OF THE DIODE, AND A CONSUMER PRODUCT | Noctiluca S.A. (PL) | 2026-01-07 | — | — | EP | disclosed |
| US-12479998-B2 | Dyes in dye aggregate systems—engineering J, K, and dye packing | BOISE STATE UNIVERSITY (US) | 2025-11-25 | — | — | US | disclosed |
| EP-4592297-A1 | AN ORGANIC BORON COMPOUND, AN ORGANIC LIGHT EMITTING DIODE COMPRISING THE ORGANIC BORON COMPOUND, A USE OF THE DIODE, AND A CONSUMER PRODUCT | Noctiluca S.A. (PL) | 2025-07-30 | — | — | EP | disclosed |
| WO-2025092905-A1 | PARP INHIBITORS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| US-12292668-B2 | Molecular aggregate for optically-pumped nonreciprocal exciton devices | BOISE STATE UNIVERSITY (US) | 2025-05-06 | — | — | US | disclosed |
| CN-114096540-B | Translocation control elements, reporter codes and other means for translocation control for nanopore sequencing | 豪夫迈·罗氏有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119431381-A | Heterocyclic compounds and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20250002497-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2025-01-02 | — | — | US | disclosed |
| WO-2002062816-A1 | NON-NATURAL NUCLEOTIDES AND DINUCLEOTIDES | CELLTECH R & D LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
| US-6399616-B1 | 4-(4-(2-(5-(1,2,4-TRIAZOL-1-YLMETHYL)-1H-INDOL-3-YL)ETHYL)-1 -PIPERAZINYL)FURO(3,2-C)PYRIDINE; COMBINED SEROTONIN REUPTAKE INHIBITOR AND PARTIAL AGONIST OF 5-HT RECEPTORS; REDUCED LATENCY; DEPRESSION | LES LABORATOIRES SERVIER (FR) | 2002-06-04 | — | — | US | disclosed |
| EP-1078928-A1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| US-5206365-A | Psychotropic heterobicycloalkylpiperazine derivatives | NEW JAMES S (US) | 1993-04-27 | — | — | US | disclosed |
| US-5116970-A | Tranquilizers | NEW JAMES S (US) | 1992-05-26 | — | — | US | disclosed |
| US-5001130-A | 1-((Amide-containing bicyclic hetero ring)-butyl-),4-heterocyclic-piperazine; anxiolytic agents; psychological disorders | BRISTOL-MYERS COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0329168-A2 | Psychotropic heterobicycloalkylpiperazine derivatives | Bristol-Myers Squibb Company (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4808595-A | REDUCTION OF PRESSURE DUE TO GLAUCOMA | MERCK & CO., INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0271273-A2 | Thieno-and furopyridine sulfonamides | MERCK & CO. INC. (US) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545700-B2 | Excitonic quantum computing via aggregate-aggregate coupling | ELAVL1, ELAVL3, NCAPH | PARP1 416/4885MAOA 4194/4885MAOB 4402/4885 |
| US-20250002497-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | F2RL3, F2R, TMPRSS4 | PARP1 430/4885MAOA 2780/4885MAOB 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.