SCHEMBL12609446

SCHEMBL12609446

CC(=O)O/N=C1\CCCc2cc(C)c(C)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.45
GAA P10253 1/20 0.45
NPC1 O15118 4/20 0.45
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
PLA2G1B P04054 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 3/20 0.38
NFKB1 P19838 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12609465 0.91 MAPT (0.45) MAPTGAANPC1KMT2AMEN1
SCHEMBL12609480 0.82 MAPT (0.55) MAPTGAANPC1KMT2AMEN1
SCHEMBL12651515 0.82 MAPT (0.51) MAPTNPC1KMT2AMEN1L3MBTL1
SCHEMBL13642351 0.80 MAPT (0.40) MAPTNPC1KMT2AMEN1L3MBTL1
SCHEMBL12609495 0.78 MAPT (0.49) MAPTGAANPC1KMT2AMEN1
SCHEMBL12651726 0.77 MAPT (0.70) MAPTNPC1KMT2AMEN1L3MBTL1
SCHEMBL13538717 0.77 MAPT (0.67) MAPTGAANPC1KMT2AMEN1
SCHEMBL5189232 0.77 LMNA (0.68) MAPTGAANPC1KMT2AMEN1
SCHEMBL12609515 0.77 LMNA (0.68) MAPTGAANPC1KMT2AMEN1
SCHEMBL21455556 0.75 MAPT (0.46) MAPTNPC1KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS MAPT 3766/4885GAA 4569/4885NPC1 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.