SCHEMBL12609495

SCHEMBL12609495

CC(=O)O/N=C1\CCCc2ccc(Br)cc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.49
KDM4E B2RXH2 1/20 0.49
NPC1 O15118 1/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
PLA2G1B P04054 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
LMNA P02545 1/20 0.45
ALDH1A1 P00352 2/20 0.43
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
PKM P14618 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
UCHL1 P09936 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12609480 0.84 MAPT (0.55) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL12651726 0.82 MAPT (0.70) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL21455556 0.80 MAPT (0.46) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL5189232 0.80 LMNA (0.68) MAPTNPC1L3MBTL1KMT2AMEN1
SCHEMBL12609515 0.80 LMNA (0.68) MAPTNPC1L3MBTL1KMT2AMEN1
SCHEMBL12609501 0.79 MAPT (0.46) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL12609446 0.78 MAPT (0.45) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL12609477 0.77 LMNA (0.63) MAPTNPC1L3MBTL1KMT2AMEN1
SCHEMBL12651672 0.76 MAPT (0.54) MAPTKDM4ENPC1L3MBTL1KMT2A
SCHEMBL12651515 0.76 MAPT (0.51) MAPTKDM4ENPC1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS MAPT 3766/4885KDM4E 114/4885NPC1 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.