SCHEMBL12609451

SCHEMBL12609451

Cc1ccc2c(c1)CCC/C2=N\OC(=O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.52
KMT2A Q03164 4/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
MEN1 O00255 3/20 0.52
PLA2G1B P04054 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
NPC1 O15118 4/20 0.52
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 5/20 0.45
TDP1 Q9NUW8 1/20 0.45
RAB9A P51151 3/20 0.44
NFKB1 P19838 2/20 0.44
NFKB2 Q00653 2/20 0.44
RELA Q04206 2/20 0.44
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12609450 0.85 MAPT (0.53) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12651512 0.85 MAPT (0.64) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12609453 0.82 MAPT (0.52) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12609449 0.80 MAPT (0.73) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL13606743 0.77 MAPT (0.45) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12609448 0.77 L3MBTL1 (0.74) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12609456 0.76 MAPT (0.54) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL12609480 0.74 MAPT (0.55) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL23878719 0.74 L3MBTL1 (0.53) MAPTKMT2AL3MBTL1MEN1PLA2G1B
SCHEMBL10041967 0.74 L3MBTL1 (0.53) MAPTKMT2AL3MBTL1MEN1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS MAPT 3766/4885KMT2A 476/4885L3MBTL1 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.