SCHEMBL12609448

SCHEMBL12609448

Cc1ccc2c(c1)CCC/C2=N\OC(=O)Cc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.74
KMT2A Q03164 5/20 0.74
ALDH1A1 P00352 4/20 0.74
MEN1 O00255 3/20 0.74
MAPT P10636 11/20 0.53
PLA2G1B P04054 1/20 0.53
ATG4B Q9Y4P1 1/20 0.53
NPC1 O15118 5/20 0.53
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.44
RAB9A P51151 4/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12651513 0.86 ALDH1A1 (0.71) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL12609453 0.84 MAPT (0.52) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL12609449 0.82 MAPT (0.73) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL13606752 0.79 ALDH1A1 (0.44) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL12609450 0.78 MAPT (0.53) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL12609451 0.77 MAPT (0.52) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL13606743 0.72 MAPT (0.45) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL13606747 0.72 MAPT (0.42) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL12609456 0.72 MAPT (0.54) L3MBTL1KMT2AALDH1A1MEN1MAPT
SCHEMBL13606745 0.71 MAPT (0.40) L3MBTL1KMT2AALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS L3MBTL1 3025/4885KMT2A 476/4885ALDH1A1 1226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.