Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323014 | 0.82 | ALDH1A1 (0.46) | SLC6A4SLC6A2CYP2D6TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL3321885 | 0.82 | RPS6KB1 (0.41) | SLC6A4SLC6A2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3321649 | 0.77 | OGA (0.39) | — | |
| SCHEMBL123222 | 0.77 | MCOLN2 (0.40) | RPS6KB1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL3322331 | 0.74 | RPS6KB1 (0.37) | RPS6KB1MEN1KMT2A | |
| SCHEMBL124745 | 0.73 | RPS6KB1 (0.43) | RPS6KB1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL3323672 | 0.71 | HTR1A (0.36) | RPS6KB1 | |
| SCHEMBL128141 | 0.71 | RPS6KB1 (0.39) | CYP3A4RPS6KB1 | |
| Hydrochloric Acid SCHEMBL3322816 | 0.69 | RPS6KB1 (0.37) | CYP3A4TSHRCYP2C19RPS6KB1MEN1 | |
| Hydrochloric Acid SCHEMBL3323677 | 0.68 | AURKA (0.40) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201002-B1 | 5-HT7 RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-03-07 | — | — | EP | disclosed |
| US-7910588-B2 | 5-HT7 receptor antagonists | ELI LILLY AND COMPANY (US) | 2011-03-22 | — | — | US | disclosed |
| US-20100197700-A1 | 5-HT7 RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197700-A1 | 5-HT7 RECEPTOR ANTAGONISTS | HTR7, HTR1A, HTR2C | SLC6A4 92/4885SLC6A2 313/4885CYP1A2 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.