Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82595 | 0.78 | MAPT (0.69) | NOTUMMAPTF2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL28340770 | 0.76 | MAPT (0.67) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL1163779 | 0.74 | NOTUM (0.64) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL311636 | 0.74 | MAPT (1.00) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL10738426 | 0.74 | NOTUM (1.00) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL382818 | 0.74 | NOTUM (0.64) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL8485436 | 0.74 | KCNJ1 (0.66) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL2054614 | 0.73 | NOTUM (0.58) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL2051536 | 0.73 | NOTUM (0.58) | NOTUMMAPTF2ALDH1A1HTT | |
| SCHEMBL10022325 | 0.73 | NOTUM (1.00) | NOTUMMAPTF2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012129452-A2 | PROPYNOIC ACID CARBAMOYL METHYL-ALMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS BASED THEREON | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-09-27 | — | — | WO | disclosed |