Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82595 | 0.98 | MAPT (0.69) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL12615985 | 0.87 | NOTUM (0.78) | MAPTALDH1A1LMNAHTTNOTUM | |
| Hydrochloric Acid SCHEMBL2897369 | 0.78 | NOTUM (0.95) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL4582384 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL311636 | 0.77 | MAPT (1.00) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL11831417 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL11118984 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL11711879 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL17993966 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM | |
| SCHEMBL1163779 | 0.77 | NOTUM (0.64) | MAPTALDH1A1LMNAHTTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116121332-A | Helicobacter pylori minimum inhibition concentration detection kit and application method thereof | 上海交通大学医学院附属仁济医院 | 2023-05-16 | — | — | CN | claimed |
| CN-113234172-B | Detection probe for syphilis specific antibody and preparation method thereof | 宜昌市第一人民医院（三峡大学人民医院） | 2022-04-22 | — | — | CN | claimed |
| CN-113234172-A | Detection probe for syphilis specific antibody and preparation method thereof | 宜昌市第一人民医院（三峡大学人民医院） | 2021-08-10 | — | — | CN | claimed |
| CN-112272586-A | Systems, methods, and interfaces for parallel processing antimicrobial sensitivity testing using different samples | 赛录科试诊断公司 | 2021-01-26 | — | — | CN | claimed |
| CN-110603333-A | Method for improved rapid antimicrobial sensitivity testing | 赛录科试诊断公司 | 2019-12-20 | — | — | CN | claimed |
| CN-112272586-B | Systems, methods, and interfaces for parallel processing of antimicrobial susceptibility tests using different samples | 赛录科试诊断公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116121332-A | Helicobacter pylori minimum inhibition concentration detection kit and application method thereof | 上海交通大学医学院附属仁济医院 | 2023-05-16 | — | — | CN | disclosed |
| CN-113234172-B | Detection probe for syphilis specific antibody and preparation method thereof | 宜昌市第一人民医院（三峡大学人民医院） | 2022-04-22 | — | — | CN | disclosed |
| CN-114258428-A | Cell structure and method for producing same | 凸版印刷株式会社 | 2022-03-29 | — | — | CN | disclosed |
| CN-113234172-A | Detection probe for syphilis specific antibody and preparation method thereof | 宜昌市第一人民医院（三峡大学人民医院） | 2021-08-10 | — | — | CN | disclosed |
| CN-113151393-A | Method for judging bacterial contamination condition of liquid strain by combining centrifugal filtration with fluorescent staining | 宁德师范学院 | 2021-07-23 | — | — | CN | disclosed |
| CN-112272586-A | Systems, methods, and interfaces for parallel processing antimicrobial sensitivity testing using different samples | 赛录科试诊断公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-110603333-A | Method for improved rapid antimicrobial sensitivity testing | 赛录科试诊断公司 | 2019-12-20 | — | — | CN | disclosed |