Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12626133 | 0.85 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12621844 | 0.83 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12663591 | 0.78 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL12621895 | 0.77 | CA12 (0.55) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL13035872 | 0.77 | HCRTR1 (0.49) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12621953 | 0.76 | POLB (0.68) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12622104 | 0.74 | POLB (0.55) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12623987 | 0.74 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL2085614 | 0.73 | MAPT (0.62) | ALDH1A1POLBMAPTDPP4DPP8 | |
| SCHEMBL12626126 | 0.73 | MAPT (0.42) | ALDH1A1MAPTDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580809-B2 | Filamin A-binding anti-inflammatory analgesic | PAIN THERAPEUTICS, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110105547-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105547-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | FLNA, FLNB, OPRK1 | L3MBTL1 3970/4885ALDH1A1 2702/4885HCRTR1 3537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.