Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012495 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KMT2ARAB9ADPP4FAAH | |
| SCHEMBL2015023 | 0.96 | DPP4 (0.48) | ALDH1A1KMT2ARAB9ADPP4FAAH | |
| SCHEMBL12628296 | 0.96 | DPP4 (0.48) | ALDH1A1KMT2ARAB9ADPP4FAAH | |
| SCHEMBL2013828 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9AFAAHMEN1 | |
| SCHEMBL12629075 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9AFAAHMEN1 | |
| SCHEMBL2010268 | 0.88 | TSHR (0.48) | ALDH1A1KMT2ARAB9AMEN1TP53 | |
| SCHEMBL12628945 | 0.88 | TSHR (0.48) | ALDH1A1KMT2ARAB9AMEN1TP53 | |
| SCHEMBL2013444 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1KMT2ARAB9AMEN1TP53 | |
| SCHEMBL12628165 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1KMT2ARAB9AMEN1TP53 | |
| SCHEMBL2010853 | 0.84 | KMT2A (0.58) | ALDH1A1KMT2ARAB9AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |