Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629075 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL2015023 | 0.92 | DPP4 (0.48) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL2012495 | 0.92 | ALDH1A1 (0.51) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL12628166 | 0.92 | ALDH1A1 (0.51) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL12628296 | 0.92 | DPP4 (0.48) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL2010268 | 0.89 | TSHR (0.48) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL12628945 | 0.89 | TSHR (0.48) | ALDH1A1KMT2ARAB9ATDP1MAPT | |
| SCHEMBL12629087 | 0.85 | ALDH1A1 (0.65) | ALDH1A1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2011747 | 0.85 | ALDH1A1 (0.65) | ALDH1A1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12628172 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |