Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | ACACA | Q13085 | 4/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | MST1R | Q04912 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628470 | 0.90 | FFAR1 (0.32) | — | |
| SCHEMBL13273761 | 0.89 | PGR (0.38) | PGRACACBACACAJAK2NTRK1 | |
| SCHEMBL12628831 | 0.88 | NOTUM (0.33) | — | |
| SCHEMBL13273307 | 0.88 | AHR (0.33) | — | |
| SCHEMBL12128939 | 0.86 | PGR (0.37) | PGRACACBACACAJAK2NTRK1 | |
| SCHEMBL12628975 | 0.86 | PTGS2 (0.34) | IL2 | |
| SCHEMBL13273763 | 0.86 | PDE3B (0.33) | PGRIL2 | |
| SCHEMBL15800885 | 0.82 | PPARG (0.35) | PGRACACBACACAPTGER4IL2 | |
| SCHEMBL12129741 | 0.81 | ALOX5 (0.34) | PGRACACBACACAPTGER4MAPT | |
| SCHEMBL13273438 | 0.81 | TDP2 (0.35) | PGRACACBACACAJAK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073615-A2 | HERBICIDAL COMPOSITION COMPRISING A PYRANDIONE HERBICIDE AND A CO-HERBICIDE | SYNGENTA LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |