Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611032 | 0.93 | SIRT2 (0.36) | ALDH1A1SIRT2SIRT1SIRT3MMP1 | |
| SCHEMBL12236087 | 0.93 | SIRT2 (0.36) | ALDH1A1SIRT2SIRT1SIRT3MMP1 | |
| SCHEMBL12236110 | 0.93 | SIRT2 (0.36) | ALDH1A1SIRT2SIRT1SIRT3MMP1 | |
| SCHEMBL12236119 | 0.93 | SIRT2 (0.36) | ALDH1A1SIRT2SIRT1SIRT3MMP1 | |
| SCHEMBL12572105 | 0.80 | SIRT2 (0.40) | ALDH1A1SIRT2SIRT1SIRT3NAAA | |
| SCHEMBL10186994 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SIRT2SIRT1SIRT3NAAA | |
| SCHEMBL12572143 | 0.80 | SIRT2 (0.40) | ALDH1A1SIRT2SIRT1SIRT3NAAA | |
| SCHEMBL12572140 | 0.80 | SIRT2 (0.40) | ALDH1A1SIRT2SIRT1SIRT3NAAA | |
| SCHEMBL13170335 | 0.80 | SIRT2 (0.40) | ALDH1A1SIRT2SIRT1SIRT3NAAA | |
| SCHEMBL13435356 | 0.80 | SIRT2 (0.40) | ALDH1A1SIRT2SIRT1SIRT3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964181-B2 | Amino acid surrogates for peptidic constructs | PALATIN TECHNOLOGIES, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-7622440-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2009-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | ALDH1A1 4870/4885SIRT2 4300/4885SIRT1 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.