SCHEMBL12629082

SCHEMBL12629082

Cc1nc2nsc(/N=N/c3cc(S(=O)(=O)N(C)C)c(O)c4cccc(NS(C)(=O)=O)c34)c2cc1C#N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12535453 0.90
SCHEMBL12629081 0.87 PLA2G7 (0.32) PLA2G7
SCHEMBL12552805 0.83 PLA2G7 (0.33) PLA2G7
SCHEMBL12629074 0.82 PLA2G7 (0.33) PLA2G7
SCHEMBL12629078 0.81 PLA2G7 (0.32) PLA2G7
SCHEMBL12552868 0.77 GLO1 (0.33) PLA2G7
SCHEMBL12629093 0.76 MEN1 (0.33)
SCHEMBL12553203 0.76 SLC22A12 (0.34) PLA2G7
SCHEMBL12535455 0.76 LRRK2 (0.32)
SCHEMBL12629061 0.74 MEN1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947815-B2 Diazenyl isothiazolo[3,4-B]pyridines as dyes FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-20080027221-A1 Azo Dye FUJIFILM CORPORATION (JP) 2008-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027221-A1 Azo Dye IK, ACMSD, ARG1 PLA2G7 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.