Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14164170 | 0.81 | KIF11 (0.50) | EDNRBEDNRAKIF11ABCC9ABCC8 | |
| SCHEMBL4906175 | 0.79 | RAB9A (0.42) | EDNRBEDNRAACHETSHRLMNA | |
| SCHEMBL31088294 | 0.78 | HTT (0.44) | EDNRBEDNRALMNAHTTNPC1 | |
| SCHEMBL316983 | 0.78 | HTT (0.44) | EDNRBEDNRALMNAHTTNPC1 | |
| SCHEMBL2947533 | 0.75 | LMNA (0.39) | EDNRBEDNRAACHELMNAHTT | |
| SCHEMBL10845930 | 0.75 | ALDH1A1 (0.44) | EDNRBEDNRAACHELMNAHTT | |
| SCHEMBL6099916 | 0.75 | HSD17B10 (0.44) | EDNRBEDNRAACHETSHRLMNA | |
| SCHEMBL28462243 | 0.75 | CYP1A2 (0.44) | EDNRBEDNRATSHRLMNAHTT | |
| SCHEMBL30406224 | 0.75 | LMNA (0.39) | EDNRBEDNRAACHELMNAHTT | |
| SCHEMBL14164168 | 0.74 | RAB9A (0.47) | LMNAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947684-B2 | anticoagulants; immunomoderators; antiinflammatory agents | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-24 | — | — | US | disclosed |