Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 10/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12633953 | 0.85 | HTT (0.49) | MMP12QPCTQPCTLP2RX3HTT | |
| SCHEMBL12633965 | 0.84 | MMP12 (0.46) | MMP12QPCTQPCTLP2RX3HTT | |
| Trifluoroacetic Acid SCHEMBL1880621 | 0.83 | CACNA1B (0.39) | — | |
| SCHEMBL12633967 | 0.82 | MMP12 (0.51) | MMP12QPCTQPCTLPOLB | |
| SCHEMBL12633984 | 0.82 | MMP12 (0.43) | MMP12QPCTQPCTLP2RX3HTT | |
| SCHEMBL12633983 | 0.81 | MMP12 (0.47) | MMP12QPCTQPCTLP2RX3P2RY14 | |
| SCHEMBL12633978 | 0.80 | QPCT (0.53) | MMP12QPCTQPCTLP2RX3HTT | |
| SCHEMBL12633971 | 0.80 | MMP12 (0.49) | MMP12QPCTQPCTLP2RX3POLB | |
| SCHEMBL12633979 | 0.80 | QPCT (0.48) | MMP12QPCTQPCTLP2RY14 | |
| SCHEMBL12634006 | 0.79 | OPRM1 (0.54) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |
| US-20090054431-A1 | NOVEL HETEROCYCLE COMPOUNDS | GLAXOSMITHKLINE LLC | 2009-02-26 | — | — | US | disclosed |
| US-20090054431-A1 | NOVEL HETEROCYCLE COMPOUNDS | GLAXOSMITHKLINE LLC | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054431-A1 | NOVEL HETEROCYCLE COMPOUNDS | OPRK1, OPRL1, OPRD1 | MMP12 2506/4885QPCT 1336/4885QPCTL 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.