Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355830 | 0.85 | SLC7A5 (0.56) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL12634549 | 0.84 | SLC7A5 (0.59) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL12301533 | 0.81 | SLC7A5 (0.65) | SLC7A5LOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL31576604 | 0.81 | SLC7A5 (0.61) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL5382573 | 0.80 | SLC7A5 (0.60) | SLC7A5LOXL2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6625943 | 0.79 | MMP13 (0.51) | NR1H4NAMPTMMP13ROCK2SMN1; SMN2 | |
| SCHEMBL879574 | 0.78 | LOXL2 (0.56) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL15876029 | 0.77 | SLC7A5 (0.54) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL15876086 | 0.77 | HIF1A (0.58) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 | |
| SCHEMBL16355834 | 0.77 | SLC7A5 (0.57) | SLC7A5NR1H4LOXL2HIF1ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |