Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.46 |
| ▸ | CHRNG | P07510 | 2/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309199 | 0.92 | GRIA1 (0.51) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL31110376 | 0.92 | GRIA1 (0.51) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL275641 | 0.87 | CHRND (0.51) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL31072235 | 0.87 | ALDH1A1 (0.48) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL13123764 | 0.87 | ALDH1A1 (0.48) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL6651722 | 0.87 | ITGB3 (0.58) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL6650599 | 0.87 | ITGB3 (0.58) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL6650597 | 0.87 | ITGB3 (0.58) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL6651343 | 0.87 | ITGB3 (0.58) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10519976 | 0.87 | ITGB3 (0.58) | CHRNDGRIA1CHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703113-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-7939611-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2011-05-10 | — | — | US | disclosed |