Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.51 |
| ▸ | CHRNG | P07510 | 2/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PCNA | P12004 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637056 | 0.87 | CHRND (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL12309199 | 0.78 | GRIA1 (0.51) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL13123764 | 0.78 | ALDH1A1 (0.48) | CHRNDCHRNA1CHRNGCHRNB1PCNA | |
| SCHEMBL31072235 | 0.78 | ALDH1A1 (0.48) | CHRNDCHRNA1CHRNGCHRNB1PCNA | |
| SCHEMBL31110376 | 0.78 | GRIA1 (0.51) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL314719 | 0.78 | FOLH1 (0.52) | GRIA1ITGB3ITGA2BPCNA | |
| Octanedioate SCHEMBL30486829 | 0.76 | ITGB3 (0.52) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| Dodecanoate SCHEMBL31683851 | 0.76 | ITGB3 (0.52) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6651343 | 0.76 | ITGB3 (0.58) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6650599 | 0.76 | ITGB3 (0.58) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180008753-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. | 2018-01-11 | — | — | US | disclosed |
| US-9782523-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160303278-A1 | DEVICES, COMPOSITIONS AND METHODS FOR BONE AND TISSUE AUGMENTATION | REVA MEDICAL, LLC | 2016-10-20 | — | — | US | disclosed |
| US-9402859-B1 | Devices, compositions and methods for bone and tissue augmentation | REVA MEDICAL, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-8702716-B1 | Devices, compositions and methods for bone and tissue augmentation | REVA MEDICAL INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-8133959-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-8124700-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110212050-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213090-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213456-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180008753-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | HACD2, HACD3, PAICS | CHRND 2509/4885CHRNA1 2867/4885CHRNG 1478/4885 |
| US-20110212050-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | IRS1, INSRR, LCP1 | CHRND 3028/4885CHRNA1 3699/4885CHRNG 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.