SCHEMBL126394

SCHEMBL126394

c1ccc(-n2c3ccccc3c3cc(-c4cccc(-c5c6ccccc6c(-c6ccc(-c7cccc8c7oc7ccccc78)cc6)c6ccccc56)c4)ccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GGPS1 O95749 1/20 0.37
PRKDC P78527 7/20 0.37
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
PLA2G10 O15496 1/20 0.36
KMT2A Q03164 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CA P42336 2/20 0.33
PIK3CB P42338 2/20 0.33
PIK3CG P48736 2/20 0.33
ALDH1A1 P00352 2/20 0.33
PDE2A O00408 1/20 0.33
PIK3C2A O00443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126554 0.97 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL15790771 0.96 ALOX5 (0.47) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL781085 0.95 ALOX5 (0.46) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL17661346 0.94 ALOX5 (0.47) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL458640 0.93 ALOX5 (0.49) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL18804979 0.93 ALOX5 (0.51) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL14979108 0.93 ALOX5 (0.51) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL457894 0.92 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL781281 0.92 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL5946939 0.92 ALOX5 (0.40) ALOX5KDM4EATML3MBTL1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-10566541-B2 Aromatic amine derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10388885-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2019-08-20 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 US disclosed
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9991455-B2 Amine compound and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-06-05 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885KDM4E 1332/4885ATM 1456/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALOX5 3494/4885KDM4E 404/4885ATM 253/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885KDM4E 258/4885ATM 736/4885
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 ALOX5 1204/4885KDM4E 256/4885ATM 397/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ATM 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.