Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310908 | 0.84 | MAPT (0.56) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| Hydrochloric Acid SCHEMBL27138709 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| Hydrochloric Acid SCHEMBL27138478 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL14853301 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL13645665 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL11991380 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL21731603 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL12640495 | 0.78 | KMT2A (0.56) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22352155 | 0.78 | SIRT1 (0.46) | SMN1; SMN2 | |
| SCHEMBL20619928 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964646-B2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |