Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23077724 | 0.81 | POLB (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL8631035 | 0.74 | MAPT (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL25877503 | 0.74 | SLC9A1 (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL8974372 | 0.72 | SLC9A1 (0.48) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL241996 | 0.70 | SLC9A1 (0.51) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL5437514 | 0.70 | SLC9A1 (0.50) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL7760804 | 0.70 | SLC9A1 (0.55) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL6905682 | 0.70 | SLC9A1 (0.50) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL10607208 | 0.67 | SLC9A1 (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL21220894 | 0.67 | SLC9A1 (0.52) | POLBMAPK1ATMDGAT1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872517-B1 | PHOTOCHROMIC FLUORENOPYRANS WITH DEFINED DIBENZO[B,D]PYRANO FUSED ATTACHMENT | RODENSTOCK GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| EP-2333028-A1 | Photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-7229576-B2 | Substituted phenanthropyrans | RODENSTOCK GMBH (DE) | 2007-06-12 | — | — | US | disclosed |