SCHEMBL7760804

SCHEMBL7760804

CC(C)(C)n1nnc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 9/20 0.55
KEAP1 Q14145 1/20 0.55
HCAR3 P49019 1/20 0.51
CYP4Z1 Q86W10 2/20 0.50
ATM Q13315 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
THPO P40225 1/20 0.50
DGAT1 O75907 1/20 0.46
GRM2 Q14416 1/20 0.43
PTPRC P08575 1/20 0.43
PTPN1 P18031 1/20 0.43
RAB9A P51151 1/20 0.42
KCNMA1 Q12791 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607208 0.84 SLC9A1 (0.52) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL13351503 0.81 SLC9A1 (0.48) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL15444316 0.81 SLC9A1 (0.53) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL13248923 0.81 SLC9A1 (0.48) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL21220894 0.80 SLC9A1 (0.52) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL10954907 0.80 SLC9A1 (0.47) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL15426054 0.80 SLC9A1 (0.47) SLC9A1KEAP1CYP4Z1ATMPOLB
SCHEMBL5217736 0.80 SLC9A1 (0.47) SLC9A1KEAP1HCAR3CYP4Z1ATM
SCHEMBL13604172 0.80 GAA (0.50) SLC9A1KEAP1HCAR3ATMPOLB
SCHEMBL5437514 0.79 SLC9A1 (0.50) SLC9A1KEAP1CYP4Z1ATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264217-B2 Surface treatment film, manufacturing method therefor, and article DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2025-04-01 US disclosed
US-12037324-B2 Biarylmethyl heterocycles BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 US disclosed
US-12037324-B2 Biarylmethyl heterocycles BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 US disclosed
US-20230348654-A1 SURFACE TREATMENT FILM, MANUFACTURING METHOD THEREFOR, AND ARTICLE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-11-02 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-11780963-B2 Multi-arm multi-claw polyethylene glycol derivative suitable for click chemistry reactions JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2023-10-10 US disclosed
US-11782062-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2023-10-10 US disclosed
US-11782062-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2023-10-10 US disclosed
US-11780963-B2 Multi-arm multi-claw polyethylene glycol derivative suitable for click chemistry reactions JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2023-10-10 US disclosed
US-20100105693-A1 Modulators of Muscarinic Receptors VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-04-29 US disclosed
US-7605160-B2 Pyrrolotriazine kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2009-10-20 US disclosed
US-20090186927-A1 TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOGS THEREOF AND METHODS OF MAKING THE SAME KOSAN BIOSCIENCES, INC. (US) 2009-07-23 US disclosed
US-20090186927-A1 TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOGS THEREOF AND METHODS OF MAKING THE SAME KOSAN BIOSCIENCES, INC. (US) 2009-07-23 US disclosed
US-20090186869-A1 Antiviral compounds GILEAD SCIENCES, INC. (US) 2009-07-23 US disclosed
US-20090186869-A1 Antiviral compounds GILEAD SCIENCES, INC. (US) 2009-07-23 US disclosed
US-20080300240-A1 PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS OMEROS CORPORATION (US) 2008-12-04 US disclosed
US-20080058337-A1 PYRROLOTRIAZINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2008-03-06 US disclosed
EP-0258021-B1 METHOD OF INHIBITING THE CORROSION OF COPPER IN AQUEOUS SYSTEMS BETZ EUROPE, INC. (US) 1989-10-18 EP disclosed
EP-0258021-A1 Method of inhibiting the corrosion of copper in aqueous systems BETZ EUROPE, INC. (US) 1988-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300240-A1 PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS PDE10A, PDE9A, PDE7A SLC9A1 3025/4885KEAP1 4663/4885HCAR3 2411/4885
US-20100105693-A1 Modulators of Muscarinic Receptors CHRM3, CHRM5, CHRM2 SLC9A1 3778/4885KEAP1 2211/4885HCAR3 66/4885
US-20090186927-A1 TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOGS THEREOF AND METHODS OF MAKING THE SAME TMSB10, TUBA1C, TUBB1 SLC9A1 3294/4885KEAP1 164/4885HCAR3 4509/4885
US-20090186869-A1 Antiviral compounds MAVS, EIF2AK2, ZC3HAV1 SLC9A1 4671/4885KEAP1 2326/4885HCAR3 4118/4885
US-11780963-B2 Multi-arm multi-claw polyethylene glycol derivative suitable for click chemistry reactions LIG1, ALK, LIG3 SLC9A1 4858/4885KEAP1 1727/4885HCAR3 1681/4885
US-12037324-B2 Biarylmethyl heterocycles ARRB1, ADRB2, ADRB1 SLC9A1 4110/4885KEAP1 603/4885HCAR3 232/4885
US-20080058337-A1 PYRROLOTRIAZINE KINASE INHIBITORS NTRK2, NTRK1, NTRK3 SLC9A1 4628/4885KEAP1 2763/4885HCAR3 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.