Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640790 | 0.81 | POLB (0.44) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL8631035 | 0.81 | MAPT (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL241996 | 0.77 | SLC9A1 (0.51) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL7760804 | 0.76 | SLC9A1 (0.55) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL6905682 | 0.76 | SLC9A1 (0.50) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL5437514 | 0.76 | SLC9A1 (0.50) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL8974372 | 0.74 | SLC9A1 (0.48) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL10607208 | 0.73 | SLC9A1 (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL21220894 | 0.73 | SLC9A1 (0.52) | POLBMAPK1ATMDGAT1SLC9A1 | |
| SCHEMBL13604172 | 0.73 | GAA (0.50) | POLBMAPK1ATMDGAT1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11485707-B2 | Deuterated compounds as rock inhibitors | FOCHON PHARMACEUTICALS, LTD. (CN) | 2022-11-01 | — | — | US | disclosed |
| US-20210070711-A1 | DEUTERATED COMPOUNDS AS ROCK INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070711-A1 | DEUTERATED COMPOUNDS AS ROCK INHIBITORS | ROCK1, ROCK2, RHOA | POLB 3243/4885MAPK1 76/4885ATM 2041/4885 |
| US-11485707-B2 | Deuterated compounds as rock inhibitors | ROCK1, ROCK2, RHOA | POLB 3243/4885MAPK1 76/4885ATM 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.