Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126626 | 0.78 | BRD4 (0.60) | ALDH1A1BRD4BRD9KDM4ENPC1 | |
| SCHEMBL19869754 | 0.77 | BRD4 (0.69) | BRD4BRD9AURKATTKAURKB | |
| SCHEMBL5174359 | 0.72 | — | — | |
| SCHEMBL25258561 | 0.71 | BRD4 (0.49) | ALDH1A1CYP3A4TDP1TP53BRD4 | |
| Benzidine SCHEMBL501952 | 0.68 | ALDH1A1 (0.85) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| Benzidine SCHEMBL27459735 | 0.68 | ALDH1A1 (0.85) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL258287 | 0.68 | CYP3A4 (1.00) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL2024128 | 0.68 | CYP3A4 (1.00) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| Benzidine SCHEMBL29021 | 0.68 | CYP3A4 (1.00) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL28842081 | 0.68 | CYP3A4 (1.00) | ALDH1A1CYP3A4TDP1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-9999625-B2 | Pyrrolobenzodiazepine compounds | FEMTOGENIX LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-20180162855-A1 | PDD AND BPD COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2018-06-14 | — | — | US | disclosed |
| US-20170050971-A1 | PYRROLOBENZODIAZEPINE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2017-02-23 | — | — | US | disclosed |
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | SPIROGEN LIMITED (GB) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | PCNA, POLL, XPA | ALDH1A1 2642/4885CYP3A4 3030/4885TDP1 269/4885 |
| US-20170050971-A1 | PYRROLOBENZODIAZEPINE COMPOUNDS | DRD1, DRD2, DRD3 | ALDH1A1 750/4885CYP3A4 739/4885TDP1 1730/4885 |
| US-20180162855-A1 | PDD AND BPD COMPOUNDS | DRD1, DRD2, XDH | ALDH1A1 869/4885CYP3A4 2392/4885TDP1 1917/4885 |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | MKI67, CCND2, CCND1 | ALDH1A1 443/4885CYP3A4 1486/4885TDP1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.