SCHEMBL12645280

SCHEMBL12645280

Cc1ccc2c(c1)CN(c1ccccc1)CO2

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VDR P11473 1/20 0.51
MAPT P10636 6/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.46
GAA P10253 1/20 0.46
ACLY P53396 1/20 0.43
ALDH1A1 P00352 2/20 0.41
RIPK1 Q13546 1/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
KCNH2 Q12809 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CYP19A1 P11511 1/20 0.35
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848287 0.91 VDR (0.54) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL15307677 0.89 VDR (0.60) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10046291 0.84 MAPT (0.43) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL25505924 0.84 NPC1 (0.41) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL15202642 0.84 MAPT (0.46) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL12162778 0.82 MAPT (0.46) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL17875592 0.82 VDR (0.47) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL20752387 0.82 VDR (0.53) VDRMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16248295 0.81 MAPT (0.45) VDRMAPTSMN1; SMN2GAAACLY
SCHEMBL28031673 0.81 MAPT (0.42) VDRMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026069-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2024-01-25 US disclosed
US-20240026069-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2024-01-25 US disclosed
US-11807767-B2 Ink composition for organic light emitting device LG CHEM, LTD. 2023-11-07 US disclosed
US-11807767-B2 Ink composition for organic light emitting device LG CHEM, LTD. 2023-11-07 US disclosed
US-20230345631-A1 PREPREG, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD JSR CORPORATION (JP) 2023-10-26 US disclosed
US-20230345631-A1 PREPREG, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD JSR CORPORATION (JP) 2023-10-26 US disclosed
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-19 US disclosed
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-19 US disclosed
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-12 US disclosed
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-12 US disclosed
US-8410202-B1 Coating compositions XEROX CORPORATION (US) 2013-04-02 US disclosed
CN-101470303-B Liquid crystal tropism agent, liquid crystal tropism film and liquid crystal display element JNC KK 2013-01-23 CN disclosed
EP-2336221-A1 Curable compositions Henkel AG & Co. KGaA (DE) 2011-06-22 EP disclosed
EP-2218748-A1 Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane Samsung SDI Co., Ltd. (KR) 2010-08-18 EP disclosed
US-20100016504-A1 CATALYTIC LOW TEMPERATURE POLYMERIZATION HENKEL AG & CO. KGAA (DE) 2010-01-21 US disclosed
US-20100016504-A1 CATALYTIC LOW TEMPERATURE POLYMERIZATION HENKEL AG & CO. KGAA (DE) 2010-01-21 US disclosed
WO-2009115488-A1 COPOLYMERIZATION METHOD HENKEL AG & CO. KGAA (DE) 2009-09-24 WO disclosed
CN-101470303-A Liquid crystal tropism agent, liquid crystal tropism film and liquid crystal display element CHISSO CORP (JP) 2009-07-01 CN disclosed
WO-2008034814-A2 BENZOXAZINE-CONTAINING FORMULATIONS POLYMERIZABLE/CURABLE AT LOW TEMPERATURE HENKEL AG & CO. KGAA (DE) 2008-03-27 WO disclosed
WO-2008034753-A1 CATALYTIC LOW TEMPERATURE POLYMERIZATION HENKEL AG & CO. KGAA (DE) 2008-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, OR51E2, ORMDL3 VDR 4122/4885MAPT 655/4885NPC1 673/4885
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, OR51E2, ORMDL3 VDR 4081/4885MAPT 799/4885NPC1 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.