SCHEMBL16248295

SCHEMBL16248295

Cc1ccc2c(c1)CN(c1ccc(S(=O)(=O)c3ccc(N4COc5ccc(C)cc5C4)cc3)cc1)CO2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
GAA P10253 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
PKM P14618 3/20 0.38
TSHR P16473 3/20 0.38
VDR P11473 1/20 0.38
ALDH1A1 P00352 3/20 0.36
RECQL P46063 1/20 0.36
USP2 O75604 2/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
CREBBP Q92793 1/20 0.36
RIPK1 Q13546 1/20 0.36
AKT1 P31749 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
HTR6 P50406 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17589746 0.86 VDR (0.46) MAPTGAASMN1; SMN2PKMVDR
SCHEMBL17589745 0.84 HTT (0.54) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL12645280 0.81 VDR (0.51) MAPTGAASMN1; SMN2TSHRVDR
SCHEMBL3674224 0.81 PKM (0.44) MAPTGAASMN1; SMN2PKMTSHR
SCHEMBL15202642 0.81 MAPT (0.46) MAPTGAASMN1; SMN2VDRALDH1A1
SCHEMBL13203361 0.80 PKM (0.49) GAAMEN1KMT2APKMTSHR
SCHEMBL12162778 0.80 MAPT (0.46) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL17703326 0.79 HSD11B1 (0.36) MAPTGAASMN1; SMN2PKMTSHR
SCHEMBL25848287 0.79 VDR (0.54) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL27945449 0.78 MAPT (0.42) MAPTGAASMN1; SMN2VDRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732225-B2 Benzoxazine resins CYTEC TECHNOLOGY CORP. (US) 2017-08-15 US disclosed
US-9732225-B2 Benzoxazine resins CYTEC TECHNOLOGY CORP. (US) 2017-08-15 US disclosed
US-20160115317-A1 BENZOXAZINE RESINS CYTEC TECHNOLOGY CORP. (US) 2016-04-28 US disclosed
US-20160115317-A1 BENZOXAZINE RESINS CYTEC TECHNOLOGY CORP. (US) 2016-04-28 US disclosed
US-9255075-B2 Benzoxazine resins CYTEC TECHNOLOGY CORP. (US) 2016-02-09 US disclosed
EP-2668238-B1 BENZOXAZINE RESINS CYTEC TECH CORP (US) 2014-11-19 EP disclosed