Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528673 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4529391 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4523092 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4536782 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4528659 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4528703 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4539447 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4538794 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4516520 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4522258 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57050893-A | — | — | None | — | — | JP | disclosed |
| CN-112321426-A | Preparation of 4-acyloxy-2-methyl-2-butenal by catalytic oxidation method | 马鞍山科思化学有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-112011388-A | Multifunctional lubricating oil and preparation method thereof | 力能石油科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-1670838-B1 | AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY | SAMYANG BIOPHARMACEUTICALS (KR) | 2015-12-09 | — | — | EP | disclosed |
| US-8349306-B2 | Hydrophilic comonomers of alkylene glycol, vinyl alcohols, vinylpyrrolidone, and/or acrylamide; hydrophobic comonoomer of lactic acid, glycolic acid, 6-hydroxycaproic acid, and/or dioxan-2-one substituted with tocopherol or cholesterol; stable micelles for delivery of anticarcinogenic agents | SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) | 2013-01-08 | — | — | US | disclosed |
| US-7879317-B2 | biocompatible amphiphilic copolymer of hydrophilic and hydrophobic blocks, and a polylactic acid derivative having a terminal carboxy metal salt; hydrophilic outer shell and hydrophobic inner core physically trap hydrophobic drug; prolonged retention time in the bloodstream on delivery | SAMYANG CORPORATION (KR) | 2011-02-01 | — | — | US | disclosed |
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| US-20080152616-A1 | Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery | SAMYANG HOLDINGS CORPORATION (KR) | 2008-06-26 | — | — | US | disclosed |
| US-7311901-B2 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORPORATION (KR) | 2007-12-25 | — | — | US | disclosed |
| EP-1448707-B1 | POLYMERIC MICELLE COMPOSITION WITH IMPROVED STABILITY | SAMYANG CORP (KR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20050201972-A1 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORPORATION | 2005-09-15 | — | — | US | disclosed |
| WO-2005040247-A1 | POLYMERIC COMPOSITION FOR DRUG DELIVERY | SAMYANG CORPORATION (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-20040253195-A1 | Polymeric michelle composition with improved stability | SAMYANG HOLDINGS CORPORATION (KR) | 2004-12-16 | — | — | US | disclosed |
| EP-1448707-A1 | POLYMERIC MICELLE COMPOSITION WITH IMPROVED STABILITY | Samyang Corporation (KR) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003033592-A1 | POLYMERIC MICELLE COMPOSITION WITH IMPROVED STABILITY | SAMYANG CORPORATION (KR) | 2003-04-24 | — | — | WO | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| JP-S5750893-A | MICROBIAL PREPARATION OF OMEGA-HALOALKANOIC ACID | KAO CORP | 1982-03-25 | — | — | JP | disclosed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |
| JP-S05750893-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080152616-A1 | Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery | CETP, ABCB4, TPRKB | TSHR 3436/4885LMNA 872/4885NFKB1 276/4885 |
| US-20040253195-A1 | Polymeric michelle composition with improved stability | MLEC, PICALM, PMP22 | TSHR 4357/4885LMNA 669/4885NFKB1 611/4885 |
| US-20050201972-A1 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | TTPA, CETP, CHKB | TSHR 2635/4885LMNA 322/4885NFKB1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.