Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 3/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 8/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765378 | 0.93 | CCKAR (0.46) | RPA1SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL14780898 | 0.90 | MGLL (0.40) | RPA1SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL12649024 | 0.88 | MALT1 (0.39) | PTGS2MGLLCCKAR | |
| SCHEMBL1764920 | 0.86 | MEN1 (0.43) | RPA1PTGS2CCKAR | |
| SCHEMBL1765529 | 0.86 | PPP1CA (0.47) | SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL14780904 | 0.84 | MALT1 (0.36) | PTGS2MGLLCCKAR | |
| SCHEMBL1765351 | 0.84 | PPP1CA (0.46) | SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL1764979 | 0.81 | CCKAR (0.51) | RPA1SLC5A1PTGS2MGLLCCKAR | |
| SCHEMBL1765030 | 0.81 | KDM1A (0.45) | PTGS2MGLL | |
| SCHEMBL1765260 | 0.81 | CCKAR (0.50) | RPA1SLC5A1PTGS2CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | AICURIS GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | TPMT, PAICS, THPO | RPA1 3978/4885SLC5A1 2409/4885PTGS2 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.