Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472102 | 0.85 | ALDH1A1 (0.45) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL4593779 | 0.80 | THRB (0.41) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29389278 | 0.80 | THRB (0.41) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL5489541 | 0.79 | SMAD3 (0.35) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29838734 | 0.79 | SMAD3 (0.35) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29838717 | 0.79 | SMAD3 (0.35) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1444923 | 0.73 | SMAD3 (0.57) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1464049 | 0.72 | SMAD3 (0.64) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL6843543 | 0.70 | HPGD (0.46) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1463198 | 0.67 | SMAD3 (0.56) | THRBRECQLTDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029091-B2 | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line | SYMPHOGEN A/S (DK) | 2015-05-12 | — | — | US | disclosed |
| US-20130203063-A1 | Procedure for Structural Characterization of a Recombinant Polyclonal Protein or a Polyclonal Cell Line | SYMPHOGEN A/S (DK) | 2013-08-08 | — | — | US | disclosed |
| US-20120322690-A1 | Anti-Rhesus D Recombinant Polyclonal Antibody and Methods of Manufacture | SYMPHOGEN A/S (DK) | 2012-12-20 | — | — | US | disclosed |
| US-8288109-B2 | Using proteolytic digestion as quality control tool in monitoring efficacy of products secreted from immunoglobulin producing cell line | SYMPHOGEN A/S (DK) | 2012-10-16 | — | — | US | disclosed |
| US-8198415-B2 | Anti-rhesus D recombinant polyclonal antibody | SYMPHOGEN A/S (DK) | 2012-06-12 | — | — | US | disclosed |
| EP-2053408-B1 | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line | SYMPHOGEN AS (DK) | 2012-03-07 | — | — | EP | disclosed |
| EP-2053408-A2 | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line | Symphogen A/S (DK) | 2009-04-29 | — | — | EP | disclosed |
| US-20090017017-A1 | Anti-rhesus d recombinant polyclonal antibody and methods of manufacture | SYMPHOGEN A/S | 2009-01-15 | — | — | US | disclosed |
| EP-1967529-A1 | Anti-rhesus D recombinant polyclonal antibody and methods of manufacture | Symphogen A/S (DK) | 2008-09-10 | — | — | EP | disclosed |
| US-20080131882-A1 | Procedure for Structural Characterization of a Recombinant Polylonal Protein or a Polyclonal Cell Line | SYMPHOGEN A/S (DK) | 2008-06-05 | — | — | US | disclosed |
| EP-1771483-A1 | ANTI-RHESUS D RECOMBINANT POLYCLONAL ANTIBODY AND METHODS OF MANUFACTURE | Symphogen A/S (DK) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006007850-A1 | ANTI-RHESUS D RECOMBINANT POLYCLONAL ANTIBODY AND METHODS OF MANUFACTURE | SYMPHOGEN A/S (DK) | 2006-01-26 | — | — | WO | disclosed |