Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25631 | 0.84 | FTO (0.50) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL5665945 | 0.82 | ALDH1A1 (0.58) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL29838734 | 0.82 | SMAD3 (0.35) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL5489541 | 0.82 | SMAD3 (0.35) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL29838717 | 0.82 | SMAD3 (0.35) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL20339897 | 0.79 | FTO (0.53) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL4593779 | 0.76 | THRB (0.41) | HPGDALDH1A1BRCA1HSD17B10RECQL | |
| SCHEMBL29389278 | 0.76 | THRB (0.41) | HPGDALDH1A1BRCA1HSD17B10RECQL | |
| SCHEMBL164316 | 0.75 | FTO (0.56) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL29501272 | 0.75 | FTO (0.56) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1697880-A | Fluorogenic enzyme assay methods and compositions | APPLERA CORP (US) | 2005-11-16 | — | — | CN | disclosed |
| US-20040146959-A1 | Fluorescent enzyme assay methods and compositions | APPLIED BIOSYSTEMS, LLC | 2004-07-29 | — | — | US | disclosed |