Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818542 | 0.94 | TSHR (0.43) | TSHR | |
| SCHEMBL6753520 | 0.88 | TSHR (0.43) | TSHR | |
| SCHEMBL4377765 | 0.86 | TSHR (0.42) | TSHR | |
| SCHEMBL8600221 | 0.85 | TSHR (0.37) | TSHR | |
| SCHEMBL125448 | 0.82 | DNM1 (0.38) | TSHR | |
| SCHEMBL11043889 | 0.82 | TSHR (0.34) | TSHR | |
| SCHEMBL11727293 | 0.78 | TSHR (0.36) | TSHR | |
| SCHEMBL11586850 | 0.78 | LMNA (0.37) | TSHR | |
| SCHEMBL15772037 | 0.77 | TSHR (0.43) | TSHR | |
| SCHEMBL15771909 | 0.77 | TSHR (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212856-B | Toluene-free silica-supported single-site metallocene catalysts from in situ formation of supported alumoxanes in aliphatic solvents | 埃克森美孚化学专利公司 | 2023-03-24 | — | — | CN | claimed |
| US-11161922-B2 | Toluene free silica supported single-site metallocene catalysts from in-situ supported MAO formation in aliphatic solvents | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-11-02 | — | — | US | claimed |
| US-11021552-B2 | Toluene free silica supported single-site metallocene catalysts from in-situ supported alumoxane formation in aliphatic solvents | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-06-01 | — | — | US | claimed |
| EP-3377541-B1 | A CATALYST COMPOSITION AND A PROCESS FOR MAKING ULTRA HIGH MOLECULAR WEIGHT POLY(ALPHA-OLEFIN) DRAG REDUCING AGENTS | SAUDI ARABIAN OIL CO (SA) | 2020-09-23 | — | — | EP | claimed |
| EP-3704164-A1 | TOLUENE FREE SILICA SUPPORTED SINGLE-SITE METALLOCENE CATALYSTS FROMIN-SITU | ExxonMobil Chemical Patents Inc. (US) | 2020-09-09 | — | — | EP | claimed |
| EP-3704163-A1 | TOLUENE FREE SILICA SUPPORTED SINGLE-SITE METALLOCENE CATALYSTS FROM IN-SITU SUPPORTED ALUMOXANE FORMATION IN ALIPHATIC SOLVENTS | ExxonMobil Chemical Patents Inc. (US) | 2020-09-09 | — | — | EP | claimed |
| CN-111356704-A | Toluene-free silica-supported single-site metallocene catalysts from in situ formation of supported MAO in aliphatic solvents | 埃克森美孚化学专利公司 | 2020-06-30 | — | — | CN | claimed |
| CN-111212856-A | Toluene-free silica-supported single-site metallocene catalysts from in situ formation of supported alumoxanes in aliphatic solvents | 埃克森美孚化学专利公司 | 2020-05-29 | — | — | CN | claimed |
| US-10301410-B2 | Catalyst composition for making ultra high molecular weight poly (alpha-olefin) drag reducing agents | SAUDI ARABIAN OIL COMPANY (SA) | 2019-05-28 | — | — | US | claimed |
| US-10287374-B2 | Method of reducing drag in a conduit | SAUDI ARABIAN OIL COMPANY (SA) | 2019-05-14 | — | — | US | claimed |
| US-5198399-A | Coordination catalyst on biodegradable support, olefin polymerization | QUANTUM CHEMICAL CORPORATION (US) | 1993-03-30 | — | — | US | claimed |
| US-5147949-A | Coordination catalyst for polymerization of alpha-olefins | EXXON CHEMICAL PATENTS INC. (US) | 1992-09-15 | — | — | US | claimed |
| US-5086025-A | Polymerization of alpha-olefins using coordination catalyst | EXXON CHEMICAL PATENTS INC. (US) | 1992-02-04 | — | — | US | claimed |
| US-5008228-A | Method for preparing a silica gel supported metallocene-alumoxane catalyst | EXXON CHEMICAL PATENTS INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0336593-A1 | Method for preparing a supported metallocene alumoxane catalyst | EXXON CHEMICAL PATENTS INC. (US) | 1989-10-11 | — | — | EP | claimed |
| WO-1989009237-A1 | METHOD OF PREPARING A SILICA GEL SUPPORTED METALLOCENE ALUMOXANE CATALYST | EXXON CHEMICAL PATENTS, INC. (US) | 1989-10-05 | — | — | WO | claimed |
| US-4433123-A | USING POLYMERIZATION CATALYST OF TITANIUM HALIDE, ALUMINUM AND PHOSPHOROUS COMPOUND | CONOCO INC. (US) | 1984-02-21 | — | — | US | claimed |
| US-4415714-A | INCORPORATING AN ETHER IN A TITANIUM TRICHLORIDE-ORGANO ALUMINUM COORDINATION CATLAYSTS; HIGH MOLECULAR WEIGHT ADDITION POLYMERS | CONOCO INC. (US) | 1983-11-15 | — | — | US | claimed |
| US-4304891-A | COORDINATION CATALYSTS, ELECTRON DONORS AND ACCEPTORS | CHISSO CORPORATION (JP) | 1981-12-08 | — | — | US | claimed |
| US-4079175-A | CATALYST COMPRISING REFORMED TITANIUM TRICHLORIDE AND ORGANOALUMINUM COMPOUND | TOYO STAUFFER CHEMICAL CO., LTD. (JA) | 1978-03-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021552-B2 | Toluene free silica supported single-site metallocene catalysts from in-situ supported alumoxane formation in aliphatic solvents | LSS, ALOX12, MUS81 | TSHR 4422/4885 |
| US-11161922-B2 | Toluene free silica supported single-site metallocene catalysts from in-situ supported MAO formation in aliphatic solvents | MAOA, MAOB, MSMO1 | TSHR 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.