Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485879 | 0.98 | ELANE (0.55) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30413621 | 0.79 | TTR (0.62) | ALDH1A1MAPTMAPK1L3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL20956398 | 0.79 | TTR (0.62) | ALDH1A1MAPTMAPK1L3MBTL1TDP1 | |
| SCHEMBL25487222 | 0.77 | TTR (0.64) | ALDH1A1MAPTMAPK1L3MBTL1TDP1 | |
| Phosphoric Acid SCHEMBL6334153 | 0.74 | ELANE (0.43) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Phosphoric Acid SCHEMBL6334073 | 0.73 | NPC1 (0.46) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Anthraquinone SCHEMBL17005080 | 0.72 | MEN1 (0.92) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Anthraquinone SCHEMBL28260408 | 0.72 | MEN1 (0.92) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Anthraquinone SCHEMBL20299926 | 0.72 | MEN1 (0.92) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Anthraquinone SCHEMBL11421894 | 0.72 | MEN1 (0.92) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9032876-B2 | Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer | FUJIFILM CORPORATION (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2343195-B1 | LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE, AND POLYMERIZABLE MONOMER | FUJIFILM CORP (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-8304171-B2 | Plate making method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-2100731-B1 | Lithographic printing plate precursor and method of lithographic printing | FUJIFILM CORP (JP) | 2012-06-20 | — | — | EP | disclosed |
| US-8187791-B2 | Lithographic printing plate precursor and plate making method thereof | FUJIFILM CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8142983-B2 | Lithographic printing plate precursor and method of lithographic printing | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |
| EP-2082875-B1 | Lithographic printing plate precursor and plate making method using the precursor | FUJIFILM CORP (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2165829-B1 | Lithographic printing plate precursor and plate making method thereof | FUJIFILM CORP (JP) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011130819-A1 | METHOD FOR ENSURING AND MONITORING ELECTROLYZER SAFETY AND PERFORMANCES | RECHERCHE 2000 INC. (CA) | 2011-10-27 | — | — | WO | disclosed |
| US-20110174179-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER | FUJIFILM CORPORATION (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2343195-A1 | LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE, AND POLYMERIZABLE MONOMER | FUJIFILM Corporation (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100075252-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2165829-A1 | Lithographic printing plate precursor and plate making method thereof | Fujifilm Corporation (JP) | 2010-03-24 | — | — | EP | disclosed |
| US-20100055607-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20090233229-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING | FUJIFILM CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090233222-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2100731-A2 | Lithographic printing plate precursor and method of lithographic printing | Fujifilm Corporation (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2082875-A1 | Lithographic printing plate precursor and plate making method thereof | FUJIFILM Corporation (JP) | 2009-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110174179-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER | SORT1, ELOVL6, SCD5 | ELANE 2277/4885RAB9A 4182/4885NPC1 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.