Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12626106 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1PTGIRSIGMAR1HTR2CSMN1; SMN2 | |
| SCHEMBL12656433 | 0.75 | POLB (0.37) | POLBKMT2AALDH1A1MEN1HTR3A | |
| SCHEMBL12626102 | 0.75 | POLB (0.68) | POLBALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL15082081 | 0.74 | CA1 (0.48) | ALDH1A1HTR3APTGIRHTR3EHTR3B | |
| SCHEMBL24937730 | 0.74 | SMN1; SMN2 (0.51) | POLBKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL20195339 | 0.71 | PTGIR (0.51) | ALDH1A1PTGIRSMN1; SMN2GRIN1GRIN2A | |
| SCHEMBL12673073 | 0.71 | CRBN (0.40) | POLBKMT2AALDH1A1MEN1HTR3A | |
| SCHEMBL20791879 | 0.71 | KDM4E (0.64) | POLBKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL19158977 | 0.70 | PTGIR (0.38) | KMT2AALDH1A1MEN1PTGIRSMN1; SMN2 | |
| SCHEMBL23178944 | 0.66 | HPGD (0.46) | POLBKMT2AALDH1A1MEN1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, OPRK1 | POLB 3278/4885KMT2A 3222/4885ALDH1A1 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.