SCHEMBL12657286

SCHEMBL12657286

CC(C)(C)c1cc(Br)c2[nH]c3c(Br)cc(C(C)(C)C)cc3c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
KIF11 P52732 3/20 0.36
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
POLB P06746 1/20 0.32
CHEK1 O14757 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732382 1.00 HIF1A (0.37) HIF1ACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL31690683 0.84 RXRB (0.37) HIF1ACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL15880058 0.84 KIF11 (0.56) KIF11GABRA1
SCHEMBL29748862 0.84 KIF11 (0.56) KIF11GABRA1
SCHEMBL29655448 0.84 KIF11 (0.56) KIF11GABRA1
SCHEMBL28105133 0.82 KIF11 (0.58) KIF11GABRA1
SCHEMBL22086118 0.80 KIF11 (0.50) KIF11HSD17B10ALDH1A1HPGDALOX15
SCHEMBL4151318 0.79 HIF1A (0.42) HIF1ACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL24484542 0.77 POLB (0.44) CYP2D6KIF11TSHRHSD17B10ALDH1A1
SCHEMBL38651956 0.76 MAPT (0.45) HSD17B10ALDH1A1HPGDALOX15CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878453-A Proton and fluoride ion double-response organic fluorescent material and preparation method thereof 三明学院 2024-11-01 CN claimed
CN-111875534-B Safe and efficient preparation method of 1, 8-diformylcarbazole 烟台大学 2022-06-17 CN claimed
CN-103848822-A 1,8-carbazole derivative, preparation method and application thereof in luminescent device WUHAN SHANGSAI OPTOELECTRONICS TECHNOLOGY CO LTD 2014-06-11 CN claimed
CN-118878453-B Proton and fluoride ion double-response organic fluorescent material and preparation method thereof 三明学院 2025-09-16 CN disclosed
CN-120118126-A Carbazole metal complex, preparation method thereof and application thereof in preparation of anti-novel coronavirus drugs 上海健康医学院 2025-06-10 CN disclosed
CN-116554154-B Thermal-induction delayed fluorescence compound, preparation method thereof and organic electroluminescent device 中国科学院长春应用化学研究所 2025-03-07 CN disclosed
CN-118878453-A Proton and fluoride ion double-response organic fluorescent material and preparation method thereof 三明学院 2024-11-01 CN disclosed
CN-118878453-A Proton and fluoride ion double-response organic fluorescent material and preparation method thereof 三明学院 2024-11-01 CN disclosed
CN-117924336-A Space charge transfer thermal activation delay fluorescent material and preparation method and application thereof 闽都创新实验室 2024-04-26 CN disclosed
US-20230309389-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
WO-2020138945-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 엘티소재주식회사 2020-07-02 WO disclosed
EP-3392257-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-10 EP disclosed
US-20180309071-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-10-25 US disclosed
EP-3392257-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2018-10-24 EP disclosed
US-20180248137-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-08-30 US disclosed
EP-2493890-B1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES SUMITOMO CHEMICAL CO (JP) 2018-03-21 EP disclosed
US-20140066290-A1 CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-06 US disclosed
US-20140066290-A1 CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-06 US disclosed
WO-2011052805-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309389-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT EMITTING DEVICE CRY1, OCIAD1, ORC3 HIF1A 1302/4885CYP1A2 693/4885CYP2D6 1321/4885
US-20180248137-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND ORC3, LEF1, OCIAD1 HIF1A 2823/4885CYP1A2 779/4885CYP2D6 803/4885
US-20180309071-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND ORC3, LEF1, OCIAD1 HIF1A 2823/4885CYP1A2 779/4885CYP2D6 803/4885
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 HIF1A 1871/4885CYP1A2 21/4885CYP2D6 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.