SCHEMBL5535430

SCHEMBL5535430

N#Cc1c2c(=O)n(-c3ccc(F)cc3)c(=O)c2c(C(F)(F)F)c2c(=O)n(-c3ccc(F)cc3)c(=O)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
ALDH1A1 P00352 6/20 0.38
MAPT P10636 3/20 0.38
GAA P10253 3/20 0.38
KMT2A Q03164 3/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 2/20 0.37
NCOA1 Q15788 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 2/20 0.35
MGLL Q99685 1/20 0.35
PIK3CD O00329 1/20 0.34
PIK3R1 P27986 1/20 0.34
TP53 P04637 1/20 0.34
PTGS2 P35354 1/20 0.34
MAPK1 P28482 1/20 0.33
HPGD P15428 2/20 0.33
GSK3A P49840 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5576251 0.81 KIF11 (0.41) KDM4ETP53
SCHEMBL5573815 0.79 MIF (0.37) KDM4ETP53TDP2
SCHEMBL5577035 0.76 ALDH1A1 (0.43) ALDH1A1LMNASMN1; SMN2MAPK1HPGD
SCHEMBL5535450 0.74 GSK3A (0.47) KDM4EPTGS2GSK3AGSK3B
SCHEMBL12660985 0.73 MGLL (0.48) KDM4EHTTSMN1; SMN2MGLLMAPK1
SCHEMBL5575206 0.72 AR (0.50)
SCHEMBL1259748 0.69 KDM4E (0.43) KDM4EALDH1A1KMT2AMEN1MGLL
SCHEMBL29328204 0.68 GSK3A (0.45) KDM4EALDH1A1MAPTGAAHTT
SCHEMBL17995365 0.68 GSK3A (0.45) PTGS2GSK3AGSK3B
SCHEMBL5535884 0.66 KAT2B (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed