Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621830 | 0.90 | ALDH1A1 (0.59) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12656050 | 0.88 | HCRTR1 (0.58) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12622132 | 0.86 | L3MBTL1 (0.51) | HCRTR1HCRTR2L3MBTL1ALDH1A1POLB | |
| SCHEMBL12622046 | 0.85 | GLA (0.60) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12626297 | 0.85 | L3MBTL1 (0.53) | HCRTR1HCRTR2L3MBTL1ALDH1A1POLB | |
| SCHEMBL12622002 | 0.85 | POLB (0.64) | HCRTR1HCRTR2L3MBTL1ALDH1A1POLB | |
| SCHEMBL12621871 | 0.83 | GAA (0.59) | HCRTR1HCRTR2L3MBTL1ALDH1A1POLB | |
| SCHEMBL12626117 | 0.83 | L3MBTL1 (0.50) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12626006 | 0.83 | L3MBTL1 (0.58) | HCRTR1HCRTR2L3MBTL1ALDH1A1POLB | |
| SCHEMBL12621845 | 0.83 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498600-B1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS INC (US) | 2016-03-02 | — | — | EP | disclosed |
| US-8580808-B2 | Filamin A-binding anti-inflammatory analgesic | Pain Therapeutic, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580808-B2 | Filamin A-binding anti-inflammatory analgesic | Pain Therapeutic, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110105484-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
| US-20110105484-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | BURNS BARBIER LINDSAY | 2010-11-04 | — | — | US | disclosed |
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | BURNS BARBIER LINDSAY | 2010-11-04 | — | — | US | disclosed |
| WO-2010051476-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS, INC. (US) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105484-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | FLNA, FLNB, OPRK1 | HCRTR1 3537/4885HCRTR2 3420/4885L3MBTL1 3970/4885 |
| US-20100280057-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | FLNA, OPRL1, FLNB | HCRTR1 1651/4885HCRTR2 1832/4885L3MBTL1 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.