Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14032363 | 0.81 | ALDH1A1 (0.68) | ALDH1A1CYP2C19CYP1A2HDAC3HDAC1 | |
| SCHEMBL10846362 | 0.79 | TSHR (0.51) | ALDH1A1CYP2C19TSHRCHRM2LOXL2 | |
| SCHEMBL18996995 | 0.78 | LMNA (0.46) | ALDH1A1CYP2C19CYP1A2MAPTMEN1 | |
| SCHEMBL13164409 | 0.77 | BCL9 (0.59) | ALDH1A1MAPTGAAPKMKMT2A | |
| SCHEMBL6932662 | 0.77 | CYP2C19 (0.61) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL6647402 | 0.76 | TSHR (0.59) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL1906879 | 0.76 | TSHR (0.55) | ALDH1A1CYP2C19TSHRCHRM2LOXL2 | |
| SCHEMBL6808768 | 0.75 | TSHR (0.58) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL8934567 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL5496017 | 0.74 | CYP2C19 (0.55) | ALDH1A1CYP2C19CYP1A2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979363-B1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-25 | — | — | EP | disclosed |