Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500692 | 0.87 | LMNA (0.56) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12665510 | 0.86 | LMNA (0.62) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10330764 | 0.85 | LMNA (0.55) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9147090 | 0.83 | EPHA2 (0.53) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8094560 | 0.83 | EPHA2 (0.53) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2087613 | 0.83 | LMNA (0.53) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6216178 | 0.81 | LMNA (0.50) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10412629 | 0.80 | LMNA (0.50) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10666385 | 0.80 | LMNA (0.81) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12665479 | 0.79 | EPHA2 (0.60) | LMNAKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124597-A1 | BORON CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | US | disclosed |
| US-7265107-B2 | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes | CUMBRE PHARMACEUTICALS INC. (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124597-A1 | BORON CONTAINING SMALL MOLECULES | BCL6B, BCL6, BLVRB | LMNA 4328/4885KMT2A 2682/4885MEN1 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.