SCHEMBL126709

SCHEMBL126709

CCOC(=O)C#CC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HDAC4 P56524 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TRPA1 O75762 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16048128 0.85 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10HDAC4HDAC6
SCHEMBL3144063 0.85 SOAT1 (0.39) ALDH1A1LMNAHSD17B10HDAC4HDAC6
SCHEMBL16049142 0.83 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10HDAC4HDAC6
SCHEMBL7614203 0.80 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1778910 0.78 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL18446 0.78 ALDH1A1 (0.53) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL16437035 0.77 HTT (0.43) ALDH1A1LMNAHSD17B10HDAC4HDAC6
SCHEMBL1513788 0.76
SCHEMBL2537922 0.75 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL23234042 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146158-A Preparation method and application of haloxyfop-methyl intermediate 浙江财和生物科技有限公司 2024-06-07 CN claimed
EP-4748445-A2 BORATE DERIVATIVE AND USES THEREOF Reistone Biopharma Company Limited (CN) 2026-05-27 EP disclosed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
WO-2026087508-A1 HYDROGELS CONTAINING COVALENTLY LINKED COFACTORS AND METHODS FOR PREPARING THE SAME HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2026-04-30 WO disclosed
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS INC (US) 2026-03-26 US disclosed
US-12583815-B2 Inhibitors of YAP/TAZ-TEAD oncoproteins, synthesis and use thereof BRIDGENE BIOSCIENCES, INC. (US) 2026-03-24 US disclosed
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-10 US disclosed
EP-4698567-A1 HYDROGELS CONTAINING COVALENTLY LINKED COFACTORS AND METHODS FOR PREPARING THE SAME Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2026-02-25 EP disclosed
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2026-02-12 US disclosed
US-12545659-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-02-10 US disclosed
US-6048869-A REDUCTASE INHIBITORS MERCK & CO., INC. (US) 2000-04-11 US disclosed
WO-2000006167-A1 TRICYCLIC COMPOUNDS MERK & CO., INC. (US) 2000-02-10 WO disclosed
WO-1999006422-A2 BASE ANALOGUES NYCOMED AMERSHAM PLC (GB) 1999-02-11 WO disclosed
US-5185025-A SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES MONSANTO COMPANY (US) 1993-02-09 US disclosed
US-5045106-A 3-phenoxypyrazole MONSANTO COMPANY (US) 1991-09-03 US disclosed
US-4964895-A Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides MONSANTO COMPANY (US) 1990-10-23 US disclosed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP disclosed
EP-0370990-A1 Herbicidal substituted pyrazoles MONSANTO COMPANY (US) 1990-05-30 EP disclosed
US-4855442-A Substituted 3-hydroxy pyrazoles MONSANTO COMPANY (US) 1989-08-08 US disclosed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545659-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK4 ALDH1A1 4348/4885LMNA 2896/4885HSD17B10 2719/4885
US-12583815-B2 Inhibitors of YAP/TAZ-TEAD oncoproteins, synthesis and use thereof YAP1, TEAD1, TEAD2 ALDH1A1 3155/4885LMNA 4369/4885HSD17B10 3091/4885
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK4 ALDH1A1 3721/4885LMNA 3765/4885HSD17B10 1867/4885
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CNR1, SCN8A, KCNH1 ALDH1A1 1090/4885LMNA 1237/4885HSD17B10 605/4885
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY MALT1, BCL6, BCL3 ALDH1A1 2586/4885LMNA 4306/4885HSD17B10 1997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.