Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12673293 | 1.00 | KMT2A (0.48) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL13953557 | 0.91 | KMT2A (0.52) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL1897441 | 0.91 | KMT2A (0.56) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL15205101 | 0.91 | MEN1 (0.51) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL1889520 | 0.91 | HSD11B1 (0.48) | HSD11B1MAOBCA1CA2GAA | |
| SCHEMBL12662082 | 0.91 | HSD11B1 (0.48) | HSD11B1MAOBCA1CA2GAA | |
| SCHEMBL13933202 | 0.81 | CA1 (0.49) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL598333 | 0.81 | CA1 (0.50) | KMT2AMEN1ESR2ESR1ATM | |
| SCHEMBL4056753 | 0.80 | CA1 (0.51) | HSD11B1CA1CA2L3MBTL1HTR1A | |
| SCHEMBL26205026 | 0.79 | ESR2 (0.62) | KMT2AMEN1ESR2ESR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935836-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | FALLIS ALEXANDER GRAHAM | 2011-05-03 | — | — | US | disclosed |
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | FALLIS ALEXANDER GRAHAM | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | JUP, CDH1, EML4 | KMT2A 2878/4885MEN1 1402/4885ESR2 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.