SCHEMBL12677643

SCHEMBL12677643

Cc1ccc(N(/N=C/c2ccc(N(c3ccc(C)c(C)c3)c3ccc(C)c(C)c3)cc2C)c2cccc(C)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
POLB P06746 1/20 0.36
EIF4H Q15056 1/20 0.36
AMY1A P0DUB6 1/20 0.35
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
EGFR P00533 2/20 0.32
CSF1R P07333 2/20 0.32
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
DHODH Q02127 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677642 0.85 MAPT (0.51) MAPTGAAMAPK1HTTPOLB
SCHEMBL4748064 0.81 MAPT (0.43) MAPTGAAMAPK1HTTPOLB
SCHEMBL9876003 0.81 MAPT (0.55) MAPTGAAMAPK1HTTPOLB
SCHEMBL15957828 0.79 ACHE (0.39) MAPTMAPK1HTTALDH1A1EGFR
SCHEMBL12677647 0.78 MEN1 (0.44) MAPTGAAMAPK1HTTPOLB
SCHEMBL13569450 0.78 ACHE (0.44) MAPTMAPK1HTTPOLBALDH1A1
SCHEMBL22317784 0.76 MEN1 (0.45) MAPTGAAMAPK1HTTPOLB
SCHEMBL13136830 0.76 ACHE (0.42) MAPTMAPK1HTTALDH1A1EGFR
SCHEMBL13569460 0.75 MAPT (0.37) MAPTHTTPOLBAMY1AALDH1A1
SCHEMBL18286391 0.75 HSD17B1 (0.40) MAPTHTTALDH1A1EGFRCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20090245867-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-01 US disclosed
US-20090245867-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-01 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed