SCHEMBL9876003

SCHEMBL9876003

Cc1cc(N(c2ccccc2)c2ccccc2)ccc1C=NN(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.55
MAPK1 P28482 3/20 0.55
GAA P10253 2/20 0.55
HTT P42858 1/20 0.55
POLB P06746 1/20 0.50
EIF4H Q15056 1/20 0.50
USP2 O75604 1/20 0.41
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
TDP1 Q9NUW8 4/20 0.38
SLC16A3 O15427 1/20 0.35
SLC16A1 P53985 1/20 0.35
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677642 0.96 MAPT (0.51) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702564 0.88 MAPT (0.51) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702562 0.88 MAPT (0.51) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702571 0.87 MAPT (0.73) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702573 0.87 MAPT (0.73) MAPTMAPK1GAAHTTPOLB
SCHEMBL4748064 0.83 MAPT (0.43) MAPTMAPK1GAAHTTPOLB
SCHEMBL10259871 0.82 MEN1 (0.47) MAPTMAPK1GAAHTTPOLB
SCHEMBL13777875 0.81 MAPT (0.49) MAPTMAPK1GAAHTTPOLB
SCHEMBL358635 0.81 MAPT (0.55) MAPTMAPK1GAAHTTPOLB
SCHEMBL358634 0.81 MAPT (0.55) MAPTMAPK1GAAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3231971-A None JP disclosed
US-8278016-B2 Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2012-10-02 US disclosed
US-8278016-B2 Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2012-10-02 US disclosed
US-20090311616-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2009-12-17 US disclosed
US-20090311616-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2009-12-17 US disclosed
EP-1146397-B1 Electrophotographic cartridge, image-forming method and image-forming apparatus MITSUBISHI CHEM CORP (JP) 2008-12-24 EP disclosed
JP-H03231971-A NEW HYDRAZONE COMPOUND NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1991-10-15 JP disclosed