Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876003 | 0.83 | MAPT (0.55) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL12677642 | 0.82 | MAPT (0.51) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL12677643 | 0.81 | MAPT (0.38) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL1702562 | 0.77 | MAPT (0.51) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL1702564 | 0.77 | MAPT (0.51) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL11321702 | 0.76 | HSD17B1 (0.36) | MAPTMAPK1HTTMEN1KMT2A | |
| SCHEMBL21695741 | 0.75 | CYP1A2 (0.39) | MAPTHTTMEN1KMT2ATDP1 | |
| SCHEMBL17810331 | 0.75 | MEN1 (0.47) | MAPTGAAMAPK1HTTPOLB | |
| SCHEMBL21173774 | 0.75 | ACHE (0.42) | MAPTMAPK1HTTTDP1CYP1A2 | |
| SCHEMBL15306320 | 0.74 | HSD17B1 (0.41) | MAPTHTTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133617-A1 | PHOTOCONDUCTOR | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-11-06 | — | — | WO | disclosed |